Science Worksheet · Grades 6–9
Genetic Mutations Worksheet
A printable science worksheet for grades 6-9 on genetic mutations. Students learn how a mutation is a change in the DNA of a gene, what can cause one, and that some are harmful while others are harmless or helpful, match eight terms to clues, and answer four short-response questions. A diagram and complete answer key are included.

Subject
Science
Grades
Grades 6–9
Skill Focus
Genetic Mutations, life science
Lesson Length
30 minutes
Lesson Overview
About this worksheet
A genetic mutation is a change in the DNA of a gene, which can be caused by a mutagen such as radiation. This worksheet teaches what mutations are, how they can be inherited, and that some are harmful while others have no effect or are helpful, with a diagram.
The reference box and Section A are on page 1. The reference box defines eight terms and shows a DNA strand with one changed spot. Section A has eight clue-matching items. Section B on page 2 has four short-response questions.
Page 3 is a complete answer key. The worksheet pairs well with the Genetics and Heredity and Punnett Squares worksheets.
How to Use This Lesson
Read the reference box and study the diagram.
Match each clue to a term in Section A on page 1.
Answer the four short-response questions in Section B on page 2.
Use the answer key on page 3 for self-check.
Pair with the Genetics and Heredity Worksheet for more practice.
Printable Resource
A classroom-ready PDF with everything in one printable resource.
Full Member Resource · Printable PDF · 3 pages · Answer Key
Genetic Mutations Worksheet
A printable science worksheet for grades 6-9 on genetic mutations. Students learn how a mutation is a change in the DNA of a gene, what can cause one, and that some are harmful while others are harmless or helpful, match eight terms to clues, and answer four short-response questions. A diagram and complete answer key are included.
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